Meta-analysis of methylprednisolone pulse therapy for Graves' ophthalmopathy
نویسندگان
چکیده
منابع مشابه
Meta-analysis of methylprednisolone pulse therapy for Graves' ophthalmopathy.
A meta-analysis was performed to evaluate the efficacy of methylprednisolone pulse therapy for Graves' ophthalmopathy. Eight studies involving 376 patients were included. A higher effective rate was found for patients treated with intravenous glucocorticoids (IVGC) over oral glucocorticoids (OGC) (risk ratio [RR] = 1.48; 95% confidence interval [CI] = 1.18-1.86). The combined IVGC and orbital r...
متن کاملEffect of methylprednisolone pulse therapy with and without alendronate on biochemical markers of bone turnover in patients with Graves' ophthalmopathy.
INTRODUCTION Immunosuppression with glucocorticoids is the method of choice in the treatment of active Graves' ophthalmopathy (GO). However, glucocorticoid therapy may have side effects, among others, it affects bone metabolism. OBJECTIVES The aim of the study was to compare the effect of methylprednisolone pulse therapy (MPPT) with and without alendronate on bone turnover markers in patien...
متن کاملCommon Immunosuppressive Monotherapy for Graves’ Ophthalmopathy: A Meta-Analysis
BACKGROUND Several immunosuppressive therapeutic regimens are widely used to treat Graves' ophthalmopathy (GO), including oral glucocorticoids (OGC), intravenous glucocorticoids (IVGC), retrobulbar injections of glucocorticoids (ROGC) and orbital radiotherapy (OR). The priority among these is unknown. This meta-analysis investigated the efficacy and tolerability of the above regimens. METHODS...
متن کاملIntravenous methylprednisolone in the treatment of Graves' ophthalmopathy.
Eleven euthyroid patients with severe Graves' eye disease were treated with intravenous methylprednisolone and followed up for six months or more by ophthalmological assessment, orbital computed tomography (CT), photographs, and antibody measurements. Papilloedema resolved in the single patient in whom it was present; visual acuity was abnormal in seven eyes initially and in only one eye after ...
متن کاملRadioiodine therapy and Graves' ophthalmopathy.
UNLABELLED Appearances of and increases in Graves' ophthalmopathy (GO) have been reported after treatment of patients with hyperthyroidism with radioiodine. We sought to determine the rates of appearance or increase in manifestations of GO in American patients treated with radioiodine for hyperthyroidism. METHODS The study population, which consisted of 76 patients (range, 10.6-72 y), include...
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ژورنال
عنوان ژورنال: Clinical & Experimental Ophthalmology
سال: 2014
ISSN: 1442-6404
DOI: 10.1111/ceo.12317